Mafunso Ofunsidwa Kawirikawiri Okhudza CBC
Zadziwika zaka 60 zapitazo, CBC, cannabichromene, ndi cannabinoid yomwe imaphunziridwa kuti ichepetse kupsinjika, kuchepetsa kuwawa, komanso kukonza thanzi.
CBC imadziwika kuti imalumikizana ndi dongosolo la endocannabinoid la thupi. ECS ili ndi udindo wowongolera machitidwe ambiri a thupi monga chilakolako, ululu, kumverera, maganizo ndi kukumbukira.
CBC imalumikizananso ndi zolandilira zina, monga TRPV1, zomwe zimatha kukhudza momwe matupi athu amayankhira ululu ndi kupsinjika.
CBC ndi cannabinoids ena monga THC ndi CBD onse amapezeka mu chomera cha cannabis, koma aliyense ali ndi mawonekedwe akeake.
CBC, monga CBD, si psychoactive ndipo sipanga "mkulu". Komabe, mosiyana ndi CBD, CBC sichimangirira mwachindunji ku ma cannabinoid receptors muubongo, koma m'malo mwake imagwira ntchito pakukulitsa zotsatira za cannabinoids ena.
THC ndi cannabinoid yodziwika bwino komanso yowerengedwa kwambiri chifukwa imayambitsa psychoactive zotsatira za chamba.
- Amachepetsa kuwawa
- Imathetsa mikangano
- Kupititsa patsogolo thanzi
- Imathandizira kuchira
- Kuwongolera maganizo
- Chotsani khungu
CBC imalumikizana ndi ECS pomanga ma cannabinoid receptors; komabe, CBC sichimangirira mwachindunji ku CB1 kapena CB2 zolandilira.
Pankhani ya zotsatira zake zenizeni, pakhala pali malipoti okhudza kusapeza bwino kwa m'mimba, monga nseru ndi kutsekula m'mimba, mwa anthu ena omwe amatenga CBC. Komabe, zizindikirozi nthawi zambiri zimaonedwa kuti ndizosowa komanso zofatsa, ndipo zimatha kuyendetsedwa mosavuta.
Pomwe Bill ya Famu ya 2018 idapangitsa kuti zinthu za CBD zikhale zovomerezeka ku United States, CBC ndi zinthu zina za CBD sizinavomerezedwe ndi FDA.
Extract Labs ndi mtsogoleri wazogulitsa za CBC zapamwamba kwambiri. Timapereka mitundu yazogulitsa kwa aliyense, monga Makapisozi a CBC kapena Mafuta a CBC.
Kodi mwakonzeka kuyang'ana dziko losangalatsa la Cannabichromene (CBC)? Cannabinoid yodziwika bwino iyi mwina sangakhale ndi mbiri yofananira ndi THC kapena CBD, koma zopindulitsa zake ndizongolonjeza. CBC ndi amodzi mwa "akuluakulu asanu ndi limodzi" cannabinoids omwe akhala akufufuza zachipatala kwa zaka zopitilira 50, ndipo ndi nthawi yoti tiziwunikira. Mu positi iyi yabulogu, tiyankha ena mwamafunso omwe amafunsidwa pafupipafupi okhudza CBC ndikuwunika zomwe adapeza, katundu wake, ndi malo pakati pa ena cannabinoids. Chifukwa chake, kaya ndinu katswiri wazodziwa zambiri za cannabis kapena mwangoyamba kumene kuphunzira za chomera chochititsa chidwichi, khalani nafe limodzi paulendo wopeza CBC yodabwitsa.
Kodi CBC ndi Chiyani Ndipo Imapezeka Kuti?
Zadziwika zaka 60 zapitazo, CBC imatengedwa kuti ndi imodzi mwa "akuluakulu asanu ndi limodzi" cannabinoids otchuka mu kafukufuku wachipatala. Sichikopa chidwi kwambiri, koma zabwino za CBC ndizolimbikitsa kwambiri.
Cannabichromene (CBC) ndiwodziwika pang'ono koma wakhala akufufuza zachipatala kwa zaka zopitilira 50. Anapezedwa mu 1964 ndi Raphael Mechoulam ndi gulu lake la ofufuza ku Hebrew University ku Israel. Ngakhale zili zopindulitsa, CBC ikadali yosadziwika poyerekeza ndi anzawo otchuka.
CBC ndi yachitatu cannabinoid yopezeka mu cannabis chomera, pambuyo pa CBD ndi THC. CBC ili ndi chiyambi chofanana ndi THC ndi CBD. Zonsezi zimachokera ku cannabigerolic acid (CBGa). Zomera za chamba zimapanga CBGa, kalambulabwalo wazinthu zina zazikulu cannabinoids kuphatikiza tetrahydrocannabinolic acid (THCa), cannabidiolic acid (CBDa), ndi cannabichromenic acid (CBCa). Awa ndi ma cannabinoids okhala ndi acidic mchira. Ndi kutentha, mamolekyu amasintha kukhala THC, CBD, ndi CBC.
Ngakhale THC ndi CBD ndizodziwika bwino komanso zodziwika bwino za cannabinoids, pali ena opitilira 100 omwe sanapezekebe ndikuphunziridwa. Mwa omwe amadziwika cannabinoids, CBC ndi amodzi mwa ang'onoang'ono, pamodzi ndi CBE, CBF, CBL, CBT, ndi CBV.
Kodi CBC Imasiyana Bwanji Ndi Cannabinoids Ena Monga THC ndi CBD?
CBC, THC, ndi CBD onse ndi cannabinoids omwe amapezeka mu chomera cha cannabis, koma aliyense ali ndi mawonekedwe apadera omwe amawasiyanitsa wina ndi mnzake.
THC ndiye cannabinoid wodziwika bwino komanso wophunziridwa kwambiri. Ndiwo omwe amachititsa kuti chamba chikhale ndi psychoactive, kupatsa ogwiritsa ntchito kumverera kwa "pamwamba". THC imagwira ntchito pomanga ma cannabinoid receptors muubongo, zomwe zimapangitsa kuti pakhale zovuta zingapo kuphatikiza kusinthika kwamalingaliro, malingaliro, ndi kuzindikira.
CBD, Komano, si psychoactive ndipo satulutsa "mkulu" wokhudzana ndi THC. M'malo mwake, zasonyezedwa kuti zili ndi ubwino wambiri wathanzi, kuphatikizapo kuchepetsa kupsinjika maganizo ndi kuthetsa kusautsika ndi kupsinjika maganizo.
CBC, monga CBD, nawonso si psychoactive ndipo samatulutsa "mkulu". Zawonedwa chifukwa cha ubwino wake. Mosiyana ndi THC ndi CBD, CBC sichimangirira mwachindunji ku cannabinoid zolandilira muubongo, koma m'malo mwake zimagwira ntchito pakukulitsa zotsatira za cannabinoids ena, makamaka THC ndi CBD.
Ngakhale CBC, THC, ndi CBD onse cannabinoids opezeka mu cannabis chomera, aliyense ali ndi katundu wapadera ndi zotsatira. CBC ndi mapindu ake achire amaganiziridwa kuti amalimbikitsidwa akagwiritsidwa ntchito limodzi ndi ma cannabinoids ena monga THC ndi CBD.
CBC sichimangirira mwachindunji ku cannabinoid zolandilira muubongo, koma m'malo mwake zimagwira ntchito pakukulitsa zotsatira za cannabinoids ena, makamaka THC ndi CBD.
Kodi Mapindu Azachipatala a CBC ndi ati?
Ngakhale CBC ili ndi maubwino amodzi, ofufuza amakhulupirira kuti imagwira ntchito mogwirizana ndi ma cannabinoids ena mu chodabwitsa chomwe chimadziwika kuti chotsatira. Ndizodziwika bwino kuti CBD ndi THC zimalimbitsa mphamvu za wina ndi mnzake, koma momwe ma cannabinoids ena amaseweretsa zotsatsira sizimamveka bwino. Komabe, zomwe zimanenedwa kuti mapindu a CBC ali ndi zotsatira zofika patali. Ndiye mafuta a CBC ndi abwino kwa chiyani kwenikweni?
Endocannabinoid Anadamide
CBC ikhoza kukhala yopindulitsa chifukwa cha momwe imalumikizirana ndi thupi lachilengedwe la endocannabinoid anandamide. Anandamide imapanga ntchito zambiri zabwino, makamaka kukulitsa malingaliro komanso kuchepetsa mantha. CBC ikuwoneka kuti imalepheretsa kutengeka kwa anandamide, kulola kuti ikhale nthawi yayitali m'magazi, motero kumawonjezera chisangalalo.
Nkhawa ndi Kuvutika Maganizo?
Kafukufuku wasayansi yemwe adafufuzidwa ngati CBC ndi THC zitha kukhala ndi kuthekera kothandizira zizindikiro zomwe zalembedwa pamwambapa poletsa enzyme inayake yotchedwa LDHA. Kuletsa uku kumaganiziridwa kuti kumachitika kudzera munjira yopanda mpikisano, zomwe zikutanthauza kuti CBC ndi THC sizikupikisana ndi zinthu zina pa chandamale chomwecho. Kafukufukuyu adagwiritsanso ntchito makina apakompyuta kuti adziwike malo omwe amamangirira CBC ndi THC ndipo adapeza kuti zinthu zonsezi zitha kumangika m'dera lomwelo, zomwe zimagwirizana ndi njira yawo yopanda mpikisano. Mwachidule, kafukufukuyu adafufuza ngati CBC ndi THC zingakhale zothandiza pothandizira zizindikiro zomwe zikufunsidwa poyang'ana enzyme inayake, LDHA. (2)
Khansara?
Kafukufuku wowona zotsatira za CBC pa khansa omwe adaphunziridwa ngati chithandizo chophatikiza CBC, THC, kapena CBD chikhoza kuchititsa kuti ma cell amangidwe komanso apoptosis yama cell. Mwachidule, kafukufukuyu adafufuza ngati kuphatikiza kwa CBC, THC, ndi CBD kumatha kukhala ndi zotsatirapo pama cell a khansa (1).
Kutupa ndi Kupweteka?
Kafukufuku wina adatsimikiza kuti CBC ndi mtundu wa cannabinoid womwe ukhoza kuyambitsa mtundu wina wa cholandirira m'thupi (CB2) mogwira mtima kuposa cannabinoid (THC). Ikuwonetsanso kuti CBC ikhoza kuthandizira kuwongolera magwiridwe antchito a cholandilira ichi. Kafukufukuyu adafufuzanso ngati kupezeka kwa CBC mu chamba kungathandize kuti pakhale chithandizo chamankhwala chamankhwala ena opangidwa ndi cannabis, makamaka chifukwa chakutha kuchepetsa kukhumudwa posintha cholandilira cha CB2. (4)
Neuroprotection?
Kafukufuku wofufuza ngati CBC ingathandize ubongo kugwira ntchito bwino. Kafukufukuyu adawonanso zotsatira za CBC pamikhalidwe yaubongo monga Parkinson's, Alzheimer's, Multiple Sclerosis, ndi kuvulala koopsa muubongo.3).
Extract Labs Tip:
Muli ndi mafuta odzola omwe mumakonda? Sakanizani Mafuta a CBC kuonjezera ubwino ndi chithandizo.
Ziphuphu?
A gulu la akatswiri omwe adawonetsa kale momwe CBD imakhudzira ziphuphu zakumaso adakulitsa kafukufuku wawo kuzinthu zina za cannabinoids, kuphatikiza CBC, ndicholinga chovumbulutsa zomwezi. Zolimbikitsa, CBC idawonetsa kuthekera komwe kungatheke ngati choletsa ziphuphu. Ziphuphu, chikhalidwe cha khungu, chimadziwika ndi kuchulukitsidwa kwa sebum ndi kutupa m'matumbo a sebaceous. Makamaka, CBC idawonetsa zotsutsana ndi zotupa komanso zomwe zingachepetse kuchuluka kwa lipid m'matumbo awa. Kuphatikiza apo, CBC idawonedwa kutsika kwa arachidonic acid (AA), chigawo chofunikira kwambiri mu lipogenesis. Ngakhale kuti kufufuza kwina kuli koyenera, kuthekera kulipo kuti CBC idzawonekere ngati mankhwala othandiza kwambiri oletsa ziphuphu m'tsogolomu.
Ndikofunika kuzindikira kuti ngakhale maphunzirowa akusonyeza ubwino wa CBC, kafukufuku wochulukirapo akufunika kuti amvetsetse zotsatira zake ndi ntchito zomwe zingatheke.
Kodi CBC imalumikizana bwanji ndi Thupi la Endocannabinoid System?
Dongosolo la endocannabinoid (ECS) ndi dongosolo lovuta m'thupi lomwe limagwira ntchito yofunika kwambiri pakuwongolera ntchito zosiyanasiyana, kuphatikiza zowawa, malingaliro, chilakolako, ndi kugona. Amapangidwa ndi endocannabinoids, zolandilira, ndi michere yomwe imagwirira ntchito limodzi kuti ikhale yokhazikika komanso yokhazikika m'thupi. Ndiye, kodi CBC imalowa bwanji mu zonsezi?
Monga cannabinoids ena, CBC imalumikizana ndi ECS pomanga ma cannabinoid receptors. Mosiyana ndi THC, yomwe imamangiriza mwachindunji ku CB1 zolandilira mu ubongo, CBC simangirira mwachindunji ku CB1 kapena CB2 zolandilira. M'malo mwake, imagwira ntchito popititsa patsogolo zotsatira za cannabinoids ena, monga THC ndi CBD, komanso kulimbikitsa milingo ya endocannabinoids m'thupi.
Zili ngati kukhala wotsogolera gulu la oimba - CBC mwina sichiyimba chida chachindunji, koma imathandizira kugwirizanitsa ndi kupititsa patsogolo machitidwe a cannabinoids ena, zomwe zimapangitsa kuti zikhale zogwirizana komanso zogwirizana. Pogwira ntchito limodzi ndi ma cannabinoids ena, CBC ikhoza kuthandizira kuthandizira chilengedwe cha thupi ndikulimbikitsa thanzi labwino.
ECS ndi dongosolo lovuta, koma kumvetsetsa momwe CBC ikugwirizanirana ndi kusakaniza kungatipatse chithunzithunzi cha ubwino wake ndi chifukwa chake ndi wofunikira kwambiri padziko lapansi la cannabinoids.
Kukhalapo kwa CBC mu chamba kungathandize kuti pakhale chithandizo chamankhwala chamankhwala ena opangidwa ndi chamba, makamaka chifukwa cha kuthekera kwake kuchepetsa kusapeza bwino posintha cholandirira cha CB2.
Kodi Pali Zotsatira Zilizonse Zodziwika za CBC?
Zikafika pakuwunika dziko la cannabinoids, ndikofunikira kuganizira zonse zomwe zingapindule komanso zotsatirapo zilizonse. Ndiye, tikudziwa chiyani za zotsatira za CBC?
Chabwino, nkhani yabwino ndiyakuti CBC imadziwika kuti ndi cannabinoid yotetezeka, yokhala ndi zotsatirapo zochepa zodziwika. Mosiyana ndi THC, CBC ndiyopanda psychoactive ndipo sipanga "mkulu" wokhudzana ndi kugwiritsa ntchito chamba. Izi zikutanthauza kuti sikungachitike kusintha kwakukulu pamalingaliro, malingaliro, kapena magwiridwe antchito.
Pankhani ya zotsatira zake zenizeni, pakhala pali malipoti okhudza kusapeza bwino kwa m'mimba, monga nseru ndi kutsekula m'mimba, mwa anthu ena omwe amatenga CBC. Komabe, zizindikirozi nthawi zambiri zimaonedwa kuti ndizosowa komanso zofatsa, ndipo zimatha kuyendetsedwa mosavuta.
Ndikofunika kuzindikira kuti ngakhale CBC ili ndi zotsatira zochepa, thupi la aliyense ndi losiyana ndipo zochita za munthu aliyense zimasiyana. Monga momwe zilili ndi mankhwala aliwonse, ndikwabwino kukaonana ndi azachipatala musanayambe kugwiritsa ntchito CBC, makamaka ngati muli ndi matenda aliwonse kapena mukumwa mankhwala aliwonse.
Ngakhale CBC imawonedwa ngati yotetezeka cannabinoid yokhala ndi zotsatirapo zochepa zodziwika, ndikofunikira nthawi zonse kusamala ndikufunsana ndi azaumoyo musanayambe kugwiritsa ntchito mankhwala atsopano. Ndipo, monga momwe zilili ndi chinthu chilichonse, ndikofunikanso kukumbukira zovuta zilizonse zomwe zingachitike ndikuwuza dokotala wanu zizindikiro zachilendo.
Kodi CBC Ndi Yovomerezeka Ndipo Ikupezeka Kuti Muzigwiritsa Ntchito Mankhwala Kapena Kusangalala?
Kuvomerezeka kwa CBC kumatha kukhala nkhani yovuta, koma musaope, tabwera kukuthandizani kuyenda pamadzi. Kuti tiyambe, ndikofunikira kuzindikira kuti kuvomerezeka kwa CBC, monga ma cannabinoids ena, kumadalira komwe muli, cholinga chogwiritsa ntchito, komanso komwe kumachokera.
Ku United States, 2018 Farm Bill Act idavomereza kulima hemp, yomwe imatanthauzidwa ngati chomera cha cannabis chokhala ndi THC yochepera 0.3%. Izi zikutanthauza kuti CBC yochokera ku hemp tsopano ndiyovomerezeka pa federal level. Komabe, malamulo a boma ndi malamulo amatha kusiyanasiyana, choncho nthawi zonse ndi bwino kuyang'ana malamulo a kwanuko musanagwiritse ntchito kapena kukhala ndi mankhwala opangidwa ndi hemp, kuphatikizapo CBC.
Ponena za kugwiritsa ntchito mankhwala, CBC sinalandirebe chilolezo kuchokera ku US Food and Drug Administration (FDA) pamtundu uliwonse. Izi zikunenedwa, mayiko ena avomereza kugwiritsa ntchito chamba chachipatala, chomwe chitha kuphatikiza CBC, pazachipatala zina. Ndikofunika kufufuza malamulo a boma lanu kuti mudziwe ngati CBC ikugwiritsidwa ntchito ngati mankhwala m'dera lanu.
Kuvomerezeka kwa CBC ndi nkhani yovuta kwambiri yomwe imadalira zinthu zambiri, kuphatikizapo malo, cholinga chogwiritsira ntchito, ndi gwero la mankhwala. Pokhala odziwa malamulo ndi malamulo a boma lanu, mutha kupewa zolakwika zilizonse zalamulo ndikupanga zisankho zanzeru pakugwiritsa ntchito CBC.
Kodi CBC Imagwiritsidwa Ntchito Motani Popanga Zinthu Zopangidwa ndi Chamba?
Kusintha kwa CBC
CBC m'zigawo ndi njira yofanana ndi CBD m'zigawo kupatula ndi cannabichromene-rich hemp. Choyamba, opanga amakoka mafuta a hemp yaiwisi kuchokera ku mbewu pogwiritsa ntchito CO2. Imatenthedwa ndi nyengo yozizira (yosiyanitsidwa ndi zinthu zosafunikira) ndi decarboxylated (kutenthedwa kuti ichotse mchira wa kaboni wa molekyulu). Chifukwa pali CBC yocheperako mu hemp kuposa CBD, kuchotsa CBC ndizovuta, ndipo mitundu yambiri ya cannabichromene imakhala ndi CBD yambiri.
Mosiyana ndi CBG, CBN ndi CBD, cannabichromene simapangidwa ndi mankhwala kukhala ufa wodzipatula. M'malo mwake, perekani ndiye mtundu wokhazikika kwambiri wa CBC extract.
Cannabinoid iliyonse ili ndi malo ake otentha, omwe amalola kuti distiller alekanitse cannabinoids pogwiritsa ntchito vacuum pressure ndi kutentha kuti atulutse distillate. Ngakhale distillate ndiye mtundu wapafupi kwambiri wamafuta oyera a CBC, cannabichromene distillate imakhala ndi ma cannabinoids ena ochepa.
CBC Products
Relief Formula CBC Mafuta Tincture
Njira imodzi yotchuka yogwiritsira ntchito CBC ndi kudzera mumafuta amtundu wa hemp, omwe ali ndi ma cannabinoids angapo, kuphatikiza CBC, CBD, ndi THC. Mafuta amtunduwu amanenedwa kuti amatulutsa "zolimbikitsa," pomwe ma cannabinoids amagwirira ntchito limodzi kuti apereke chidziwitso chokwanira komanso chothandiza.
Makapisozi a Fomula Yothandizira CBC
Monga mawonekedwe athu amafuta, CBC softgels ali ndi mlingo womwewo wa CBC ku CBD mu botolo lililonse (600 mpaka 1800, motsatana). Makapisozi ali ndi maubwino angapo, makamaka kuti ma softgels ndi opangidwa kale, ochezeka komanso osakoma.
Kuwonjezera CBC Cannabinoids ku Regimen Yanu
Poyamba chizolowezi chazomera chofunikira pazomera, ndikofunikira kuyesa zinthu zatsopano ndikumvetsera thupi lanu nthawi iliyonse. Ngakhale kuti CBD ingakhale ikunyenga yokha, muthanso kuwona kuti kuyesa ma cannabinoids ngati CBC kumabweretsa zotsatira zabwino.
CBC ndi cannabinoid yodalirika yomwe iyenera kuganiziridwa pazabwino zake. Ndi chikhalidwe chake chosagwiritsa ntchito psychoactive komanso kuthekera kochepetsera kupsinjika, kusapeza bwino, ndi zinthu zina zodabwitsa CBC ndiwowonjezera kudziko la cannabis. Ndiye bwanji osayesa kuti muwone ngati ikugwira ntchito kwa inu? Ndi mapindu ake omwe angakhalepo komanso zinthu zosiyanasiyana zomwe zilipo, CBC ndiyofunikira kufufuzidwa.
Ngati mwakhala mukuyesera zinthu zosiyanasiyana koma sizinaphule kanthu, gulu lathu la akatswiri a m'nyumba lili pafupi, okonzeka kuyankha mafunso aliwonse. Kaya mukungoyamba kumene ndikuyang'ana mayankho pazomwe mungayembekezere kapena katswiri wa CBD akungofuna kukonza zomwe mumachita, tili pano!
Maupangiri ena a CBD | CBDa ndi CBGa Cannabinoids
Kodi CBDa ndi Chiyani CBGa?
Ntchito Zosimbidwa
1. Anis, Omer, et al. "Cannabis-Derived Compounds Cannabichromene ndi Ī9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Yogwirizana ndi Kuletsa Kusamuka Kwa Maselo ndi Cytoskeleton Organization." MDPI, 2021, https://www.mdpi.com/1420-3049/26/2/465. Adafikira pa 23 February 2023.
2. Martin, Lewis J., et al. "Cannabichromene ndi Ī9-Tetrahydrocannabinolic Acid Yodziwika Monga Lactate Dehydrogenase-A Inhibitors ndi Silico ndi Vitro Screening." Zofalitsa za ACS, 2021, https://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.0c01281. Adafikira pa 23 2 2023.
3.OlĆ”h A;Markovics A;SzabĆ³-Papp J;SzabĆ³ PT;Stott C;Zouboulis CC;BĆrĆ³ T; "Kusiyanasiyana kwa Ma Phytocannabinoids Osankhidwa Osakhala a Psychotropic pa Ntchito Za Sebocyte Zaumunthu Zimakhudza Kuyambitsa Kwawo Pakhungu Louma / Seborrhoeic ndi Chithandizo cha Ziphuphu." Dermatology Yoyesera, pubmed.ncbi.nlm.nih.gov/27094344/. Inafikira pa 14 Oga. 2023.
4. Shinjyo, Noriko, ndi Vincenzo Di Marzo. "Zotsatira za cannabichromene pama cell achikulire a neural stem / progenitor." PubMed, 2013, https://pubmed.ncbi.nlm.nih.gov/23941747/. Inafikira pa 23 February 2023.5. Udoh, Michael, et al. "Cannabichromene ndi cannabinoid CB2 receptor agonist." British Pharmacological Society, 2019, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14815. Adafikira pa 23 2 2023.
